Cold sore



Definition

Cold sores are small red blisters, filled with clear fluid, that form on the lip and around the mouth. Rarely, they form on the roof of the mouth. Cold sores are caused by the herpes simplex virus type 1 (HSV-1), which lives inside nerve tissue. Despite their name, cold sores have nothing to do with colds. The herpes simplex virus type 1 should not be confused with the herpes simplex virus type 2 (HSV-2), which most often causes genital herpes.

Description

There are eight different kinds of human herpes viruses. Only two of these, herpes simplex types 1 and 2, can cause cold sores. It is commonly believed that herpes simplex virus type 1 infects above the waist and herpes simplex virus type 2 infects below the waist. This is not true. Both herpes virus type 1 and type 2 can cause herpes lesions on the lips or genitals, but recurrent cold sores are almost always type 1.

The sores can appear within days or weeks or even years following the first exposure to the virus. The first time symptoms appear they are usually more intense than later outbreaks. For example, some children experience more pain at the blister site or even flu-like symptoms, including swollen glands, fever , or sore throat . Medical names for cold sores include oral herpes, labial herpes, herpes labialis, and herpes febrilis.

Transmission

Herpes simplex virus is transmitted by infected body fluids (such as saliva) when they contact breaks in another person's skin or mucous membranes. Newborns may become infected during delivery through an infected birth canal. HSV-1 can be passed to children by parents, nurses, and caregivers who fail to practice careful hand washing. Children with burns , eczema, or diaper rash or those who are immunosuppressed are highly susceptible to the herpes virus.

VIRUS VERSUS BACTERIA Viruses behave differently than bacteria. While bacteria are independent and can reproduce on their own, viruses enter human cells and force them to make more viruses. The infected human cell dies and releases thousands of new viruses. The cell death and resulting tissue damage causes the cold sores. In addition, the herpes virus can infect a cell, and instead of making the cell produce new viruses, it hides inside the cell and waits. The herpes virus hides in the nervous system. This action is called latency. A latent virus can wait inside the nervous system for days, months, or even years. At some future time, the virus "awakens" and causes the cell to produce thousands of new viruses that cause an active infection.

Latent and active infection is understood by considering the cold sore cycle. The first infection is the primary infection. The primary infection is controlled by the body's immune system and the sores heal. Between active infections, the virus is latent. At some point in the future, latent viruses become activated and once again cause sores or recurrent infections. Although it is unknown what triggers latent virus to activate, several conditions bring on infections. These include stress, illness, fever, fatigue, exposure to sunlight, menstruation , and diet.

Demographics

The herpes simplex virus is widespread in children. Thirty-five percent of five-year olds carry HSV-1 antibodies. A primary infection commonly occurs by the time a child reaches age five. These viral infections are more common in lower socioeconomic groups.

Nearly 80 percent of the general population carry the herpes simplex virus that causes cold sores, and 60 million have outbreaks once or more in a year. Most infants and children harbor the herpes virus before age ten. Interestingly enough, only 20 percent to 25 percent of those carrying the virus ever gets symptoms (break out in cold sores).

Causes and symptoms

While anyone can have the herpes virus infection, not everyone will show symptoms. The first symptoms of herpes occur within two to 20 days after contact with an infected person. Symptoms of the primary infection are usually more severe than those of recurrent infections. The primary infection can cause symptoms like other viral infections, including fatigue, headache , fever, and swollen lymph nodes in the neck.

Typically, 50 to 80 percent of children with oral herpes experience a prodrome (symptoms of oncoming disease) of pain, burning, itching , or tingling at the site where blisters will form. This prodrome stage may last a few hours or one to two days. The herpes infection prodrome occurs in both the primary infection and recurrent infections.

In 95 percent of the patients with cold sores, the blisters occur at the outer edge of the lips, which is called the vermillion border. Less often, blisters form on the nose, chin, or cheek. Following the prodrome, the disease process is rapid. First, small red bumps appear. These quickly form fluid-filled blisters.

Causes of cold sores in children

Infants are most likely to get a cold sore because someone with an active virus kisses them. The cause can even be a kiss from someone who did not have a visible sore but had the virus in his or her saliva. A baby may also get the herpes virus passing through the birth canal if the mother has genital herpes.

Once a child gets the virus, it stays in his body permanently, hiding in nerve cells near the ear. In some children, the virus lies dormant and never causes harm. In others, it periodically wakes up and triggers cold sores. Nobody knows what stirs the virus into action, but stress, fever, colds, and sunburn encourage outbreaks. Rich foods such as chocolate, food allergies , or hormonal changes may also cause outbreaks in children and adolescents.

Symptoms of cold sores in infants

The first symptoms of cold sores in infants are swollen gums and sore mouth. A few days later, there is a cluster of small blisters on or near the lips that turn into a shallow, painful sore. The breakout is often accompanied with fever and swollen lymph glands in the neck. In a few days the sore will crust and slowly disappear. The whole flare-up lasts about seven to ten days. The next time the infant has an outbreak the blister is the first symptom, not the swollen gums and painful mouth. If not treated, recurring outbreaks may last longer.

Stages of cold sores in children and adolescents

Cold sores, untreated, can last up to 14 days. Children often feel the tingling at the site before the sore appears. Parents should begin the treatment at the first sign of tingling or redness, which can reduce the time to two to four days. Beginning treatment after the blister appears can also significantly reduce the time and degree of pain. The following describes the stages of a cold sore:

  • Day 1: Prodrome (tingle) stage: Before a blister appears, the child usually feels a tingling, itching, or burning sensation beneath the skin, usually around the mouth or the base of the nose. This is the best time to start treatment.
  • Days 2 to 3: The blister or blisters appear. Children usually have one or several blisters on or around the moth, most often at the border of the lip and the skin on the face. Cold sores occasionally occur on the roof of the mouth.
  • Day 4: Ulcer or weeping stage: The blister opens, revealing a reddish area. The child is most contagious and in the most pain at this point.
  • Days 5 to 8: Crusting stage: The blisters dry up, and a crust forms which is yellow or brown in color. Children should be told not to pick at this crust.
  • Days 9 to 14: Healing stage: A series of scabs form over the sore, each smaller than the previous one until the cold sore is healed.

When to call the doctor

The HSV-1 virus can cause ocular herpes, a serious eye infection affecting the cornea (the clear window) of the eye, which can threaten vision and needs immediate medical attention and treatment. When a baby or child has a cold sore, parents should do all they can to keep them from touching their eyes. If a painful sore appears on the child's eyelid, eye surface, or on the end of his nose, call the pediatrician right away. The child may need antiviral drugs to keep the infection from scarring the cornea. Ocular herpes can weaken vision and even cause blindness.

Some children have a serious primary (first episode) herpes infection called gingivostomatitis, which causes fever, swollen lymph glands, and several blisters inside the mouth and on the lips and tongue that may form large, open sores. These painful sores may last up to three weeks and can make eating and drinking difficult. Because of this problem, young children with gingivostomatitis are at risk for dehydration . Children with this condition should be seen by a doctor.

Most infants have protection for at least six months from HSV-1 by antibodies they received from their mothers. But if a newborn gets a cold sore, the pediatrician should be called right away.

If the immune system of children is compromised because of cancer treatment or AIDS , they could have more serious problems with the herpes virus. Parents should let the doctor know if these health conditions exist.

Children with a history of frequent herpes flare-ups who spend time skiing or on the beach should call a doctor for a prescription for starting oral anti-herpes medication (pills) before such outings and then using sunscreen while they are outside. These precautions can prevent most outbreaks.

Diagnosis

Cold sores are diagnosed by review of symptoms, physical examination, and history. The diagnosis is confirmed by various viral tests. A Tzanck or Papanicolau smear may be done. A positive smear cannot distinguish between varicella zoster virus and HSV-1, and a negative smear does not rule out HSV infection. Tissue culture provides a more reliable method of diagnosis. Cells killed by the herpes virus have a certain appearance under the microscope. Laboratory blood test looks for the virus or to confirm the presence of antibodies that fight the virus.

Approximately 85 percent of active herpes infections are without symptoms. When the symptoms do appear, they have the following sequence:

  • burning, itching, or tingling at the site before the sore appears
  • clusters of fluid-filled vesicles ulcerate, dry, and crust
  • lesions dry and crust within seven to ten days
  • usually one or two lesions present on the lips, tongue, gingival, or buccal mucosa
  • puritis (itching) and pain

Treatment

There is no cure for herpes virus infections. Antiviral drugs are available that have some effect on lessening the symptoms and decreasing the length of herpes outbreaks. There is evidence that some may also prevent future outbreaks. These antiviral drugs work by interfering with the reproduction of the viruses and are most effective when taken as early in the infection as possible. For the best results, drug treatment should begin during the prodrome stage before blisters are visible. Depending on the length of the outbreak, drug treatment could continue for up to ten days.

Antiviral pills such as acyclovir (Zovirax), famciclovir, (Famvir), and valacyclovir (Valtrex) can cancel an outbreak and help prevent recurrent outbreaks. Acyclovir (Zovirax) is the drug of choice for herpes infection and can be given intravenously or taken by mouth. A liquid form for children is also available. Acyclovir is effective in treating both the primary infection and recurrent outbreaks. When taken by mouth, acyclovir reduces the frequency of herpes outbreaks.

Antiviral creams Zovirax and Denavir should be applied within the first 24 hours of feeling the tingling or discomfort, before the plaster erupts. The duration of the outbreak can be shortened by a day or two. Antiviral creams are not as effective as the pills.

During an outbreak, sores should be washed once or twice a day with warm, soapy water, and gently patted dry. Over-the-counter lip products that contain the chemical phenol (such as Blistex Medicated Lip Ointment) and numbing ointments (Anbesol) help to relieve cold sores. A bandage over the sores protects them and prevents spreading the virus to other sites on the lips or face.

Close-up view of a cold sore, caused by herpes simplex virus, on a patients mouth. ( Kenneth Greer/Visuals Unlimited.)
Close-up view of a cold sore, caused by herpes simplex virus, on a patient's mouth.
(© Kenneth Greer/Visuals Unlimited.)

Acetaminophen (Tylenol) or ibuprofen (Motrin, Advil) may be necessary to reduce pain and fever.

Alternative treatment

Cold sores in infants and children will go away on their own, but there are measures that will help the child feel better:

  • To ease the pain, apply ice to the sore, or if the doctor approves, give the baby a mild pain reliever, such as ibuprofen or acetaminophen. (Do not give aspirin to a baby; it could trigger Reye's syndrome. This is a rare but potentially life-threatening illness.) Choices for pain relief include medication, ointments, or mouth rinses recommended by the pediatrician. Parents may also use Oragel, an ointment often used for canker sores or teething.
  • Avoid giving the child spicy, salty, or sour foods, and foods with acid (oranges and grapefruits), which can irritate the open sore.
  • Apply a water-based zinc ointment such as Desitin. It helps dry out the sore so it can heal faster.
  • Extra sleep and plenty of liquids to drink can help.

Adolescents can learn to manage their own outbreaks. They can take the following steps:

  • Use over-the-counter pain relievers, such as acetaminophen (Tylenol) or ibuprofen (Motrin, Advil).
  • Avoid squeezing or picking the blister.
  • Apply ice to ease the pain.
  • Acidophilus pills may be helpful in treating cold sores. L-lysine is an amino acid widely advertised to treat cold sores. Conflicting medical opinions exist about its effectiveness.

Nutritional concerns

If children are prone to recurrent viral infections, parents should review their eating habits. The children should avoid foods and drinks that are proven suppressors of immunity (foods high in sugar, caffeine , and alcohol content) and have regular meals with plenty of fresh vegetables and fruits and whole-grain products. Some foods may be increased or reduced for specific types of viral infections. For herpes, foods containing the amino acid arginine (nuts and seeds) need to be reduced, and those containing the amino acid lysine (yogurt and cottage cheese) need to be increased. Immune system health in children can also benefit from a wide range of vitamins and minerals as nutritional supplements. Vitamin B complex and vitamins A, C, and E are the most important supplements.

Prognosis

Anyone can become infected with the herpes virus. Once infected, the virus remains latent in the body for life. It lives in nerve cells where the immune system cannot find it. The herpes virus lies dormant in the nerves of the face and is reactivated by sunburn, a recent viral illness (cold or flu), and periods of stress. Cold sores spread from person to person by direct skin-to-skin contact.

The highest risk for spreading the virus is the time period beginning with the blisters and ending with scab formation. However, infected people need not have visible blisters to spread the infection since the virus may be present in the saliva without obvious oral lesions.

Most children experience fewer than two recurrent outbreaks of cold sores each year; some have frequent outbreaks and others never experience outbreaks. Most blisters form in the same area each time and are triggered by the same reasons (such as stress, sun exposure, etc.).

Prevention

Cold sores are contagious. As of 2004 there were no herpes vaccines available, although herpes vaccines were in research and development. Avoiding close contact with people shedding the virus is the best way to prevent primary herpes. Several practices can reduce reoccurring cold sores and the spread of virus:

  • Parents should teach children not to share drinks, food, or eating utensils, and not to exchange kisses with someone with mouth sores.
  • When parents have an outbreak, they should avoid kissing their children (and other adults).
  • Parents should be watchful of infected children and not allow them to share toys that may be put into the mouth. Toys that have been in the child's mouth should be disinfected before other children play with them.
  • Parents should be especially careful with infants; they should not kiss the eyes or lips of a baby who is under six months old. The child's eyes and genitals are particularly susceptible to the herpes virus. They should keep the child from picking at a cold sore as much as possible.
  • To keep from spreading the infection to other parts of the child's body or giving the virus to someone else, parents and caregivers should wash their hands and the child's hands often, especially after feedings and diaper changes.
  • The child should be protected from the sun, since exposure to sunlight can trigger an outbreak. If the child is outside on a sunny day, generously apply sunscreen and lip balm that contains sun block before prolonged exposure to the sun. Sun block should be used during both winter and summer months, to help prevent cold cores. Wearing a hat with a large brim is also helpful.
  • Parents should wear gloves when applying ointment to a child's sore. They should remove gloves and wash hands before and after changing diapers.
  • Antibiotic ointments may be used to treat secondary bacterial infection of lesions. Parent should avoid using steroid creams or gels on a suspected herpes infection because these agents could make the infection worse.
  • Parents should maintain good general health. A healthy diet, plenty of sleep, and exercise help to minimize the chance of getting a cold or the flu, which may bring on cold sores. Also, good general health keeps the immune system strong; this helps to keep the virus in check and prevents outbreaks.

Parental concerns

The child with a herpes infection is usually miserable and needs generous cuddling and comfort in spite of the infection. Parents of children who get cold sores should be aware of early symptoms and be ready to treat the sore in the first couple days. They should also keep in mind the prevention tips mentioned above. Parents should call the child's pediatrician if the child has not had a cold sore before, especially in the case of babies.

KEY TERMS

Antiviral drug —A medication that can destroy viruses and help treat illnesses caused by them.

Contagious —The movement of disease between people. All contagious disease is infectious, but not all infections are contagious.

Herpetic gingivostomatitis —A severe oral infection that affects children under five years of age; vesicles and ulcerations, edematous throat, enlarged painful cervical lymph nodes occur; chills, fever, malaise, bed breath, and drooling.

Latent virus —A nonactive virus that is in a dormant state within a cell. The herpes virus is latent in the nervous system.

Oral lesions —A single infected sore in the skin around the mouth or mucus membrane inside of the oral cavity.

Prodrome —Early symptoms that warn of the beginning of disease. For example, the herpes prodrome consists of pain, burning, tingling, or itching at a site before blisters are visible while the migraine prodrome consists of visual disturbances.

Recurrence —The return of an active infection following a period of latency.

Reye's syndrome —A serious, life-threatening illness in children, usually developing after a bout of flu or chickenpox, and often associated with the use of aspirin. Symptoms include uncontrollable vomiting, often with lethargy, memory loss, disorientation, or delirium. Swelling of the brain may cause seizures, coma, and in severe cases, death.

Secretion —A substance, such as saliva or mucus, that is produced and given off by a cell or a gland.

Resources

BOOKS

Health and Healing the Natural Way: Energize Your Life. Pleasantville, New York: The Reader's Digest Association, Inc., 2000.

Parker, Philip M., et al. Cold Sores: A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References. Boulder, CO: netLibrary, 2003.

PERIODICALS

Novatnack, Ellen, and Steven Shchweon. "Herpes: A bigger problem than you think." RNMagazine 65 (June 2002):31-37.

WEB SITES

"Herpes labialis (oral Herpes simplex)." MedlinePlus , July 12, 2004. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000606.htm (accessed December 14, 2004).

Aliene S. Linwood, RN, DPA, FACHE Belinda Rowland, PhD



User Contributions:

1
hannah xuereb
Report this comment as inappropriate
Jul 29, 2006 @ 11:11 am
my daughter is 15 months old she had coldsores come up about 3 months ago and ended up in hospital she evently got better. They have come up again been to the doctors they gave her zarvirax its been about a week her temp has gone as high as 40.2 keep giving her fluids as she is not eating i am worried as she is small for her age anyway do u have any suggestions?
2
Dawn
Report this comment as inappropriate
May 6, 2008 @ 8:20 pm
My 4 1/2 year old son has recently complained of his mouth hurting, yet there was nothing visually there. The day care provider called and informed me that he has a "cold sore". Now, i don't know anyone that has a cold sore at this time, and he has not been around kissing anyone that i am aware of. I was just wondering if cold sores can be inherited?? I only ask this because my son's father has a history of cold sore/ canker sore breakouts and want to know if i have to be prepared for my son to have them as well.
3
Report this comment as inappropriate
Feb 24, 2017 @ 10:10 am
i am anna jason, I was diagnosed HSV1 genital in September of 2015. My partner's STD screening was HSV1 positive but he was asymptomatic and did not believe he had an ethical responsibility to disclose. 80% of the population is HSV1 positive. I had little knowledge HSV1 genital until I was diagnosed. I suffered a painful prodromal state, severe stomach cramps, itching, spinal neuralgia followed by an outbreak every month. i have been going for treatment all the time, until i search online about the cure and i saw several commenting about doctor omole having the cure and i contact him about the cure. he told me to pay for the herbal medicine which i did and after making the payment, he sent me the herbal medicine and i receive the medicine within 3 days. i use the medicine twice a day ( morning and at night before i go to bed). after using the medicine for a week and few days, i go back to hospital and i was negative. i decide to share this because i know a lot of people are herpes positive and they're looking for the cure. kindly contact doctor omole for your own cure and also thank him for my behalf for getting me back to my normal life again. you can contact him on doctoromoleherbalhome@gmail.com
4
RUTH MARIS
Report this comment as inappropriate
Feb 24, 2017 @ 4:16 pm
All thanks to Dr Alli for curing my HERPES SIMPLEX VIRUS / HPV with his herbal medicine, i do not have much to say but with all my life i will for ever be grateful to him and God Almighty for using Dr Alli to reach me when i thought it was all over, today i am happy with my life again after the medical doctor have confirmed my HERPES SIMPLEX VIRUS / HPV of 5 is gone,i have never in my life believed that HERPES SIMPLEX VIRUS could be cured by herbal medicine. so i want to use this means to reach other persons who have this disease by testifying the power of Dr Alli that all hope is not lost yet, try and contact him by any means for any kind of disease with his email: ( allispellhelp1@gmail.com ) or +2348100772528.
5
brittany yate
Report this comment as inappropriate
Feb 24, 2017 @ 4:16 pm
hello everybody,
i don't just know the reason why some people is finding it difficult to believe that there is a cure for Herpes, i have been suffering from Herpes since last three years with my boyfriend but today i am happy that am cure from it with the herbal medicine of DR SEBI the great healer,i was browsing the internet searching for help when i came across a testimony shared by someone on how DR SEBI cure his herpes i was so much in need of getting his treatment but after all DR SEBI brought a smile to my face with his herbal medicine. i am so much happy today that we have someone like this great healer out there, so my people out there kindly contact this great healer on his website: please sir keep your good work cause there are people out there who is in need of your healing medicine.once more contact him now: drsebispelltemple@gmail.com you can call him or whatsApp his number +2348153863900 thanks DR SEBI for your great works this are also the diseases DR SEBI cures

HIV/AIDS
HERPES
LOW SPERM COUNT
DIABETES
ASTHMA
SYPHLIES
6
livenus collins
Report this comment as inappropriate
Feb 24, 2017 @ 4:16 pm
TESTIMONY OF HOW I GOT CURED FROM HERPES SIMPLEX VIRUS
This is real take it serious, i am livenus collins, i am from USA. Who will believe that a herb can cure herpes, i never believe that this will work, i have spend a lot getting drugs from the hospital to keep me AND my son healthy, it got to a time that i was waiting for is death to come because i was broke, one day i hard about this great man called DR.UDURO who is well know for Herpes, HIV, and Cancer cure, i decided to email him I didn't believe him that much, I just wanted to give him a try, he replied my mail and Needed some Information about me, then I sent them to him, he prepared a herbal medicine (CURE) and sent it through Online Courier Service for delivery, he gave my details to the Courier Office. they told me that 3-5 days I will receive the package and after receiving it, i took the medicine as prescribed by him at the end of the one week, he told me to go to the hospital for a check up, and i went, surprisingly after the test the doctor confirm me Herpes simplex virus negative, and my son i thought it was a jockeing, i went to other hospital and was also negative, thank you for saving our lifes, I promise I will always testify of your good works. if you are herpes simplex virus patient, contact him and I am sure you will get cured, contact him via: drudurohaberahome@gmail.com CALL OR WHATSAPP HIM TRUE HE CELL PHONE +2348138634433
THESE ARE THE THINGS DR.UDURO CURE
. HERPES
. HIV/AIDS
. CANCER
. DIABETIES
. LASSA FEVER
. GONORRHEA
. MENOPAUSE DISEASE
. EPILEPSY
. ASEPSIS
Email him now via: drudurohaberahome@gmail.com You can also call or Whatsap him on +2348138634433.
7
Susan
Report this comment as inappropriate
Feb 24, 2017 @ 5:17 pm
Good day viewers.. please just read this, some times we just need to give a try of herbal Medicine to see for our self. I am very happy today that i do not listen to what people say if not i would have been a dead man by now. I was infected with HERPES SIMPLEX VIRUS in 2014, i went to many hospitals for cure but there was no solution, so I was thinking how can I get a solution out so that my body can be okay. One day I was in the river side thinking where I can go to get solution. so at that moment i was doing some research about remedy for herpes on my cell phone, so i came across an articles about a lady testifying on how she get cured by the help of a doctor called Odoma, so i have to write down the email contact of the doctor that she recommended which is ( odomaspelltemple@outlook.com ) on a very good day i decide to write to this doctor and explain how this virus is killing me slowing, after introducing myself to this doctor after some time i got a reply back from him, and he told me the important of his herbal medicine also how he has cure HERPES SIMPLEX VIRUS and all kinds of virus, He told me all the things I need to do and also give me instructions to take, which I followed properly. Before I knew what gradually my body was getting recovery and i was feeling so different than ever after two weeks the HERPES SIMPLEX VIRUS that was in my body got vanished. so if you are also heart broken and also need a help, you can also contact him Via Email (odomaspelltemple@outlook.com ) and give a try i promise if you can stay in touch with Him through his contact email address stated here correctly you wont miss out okay here is the Email once again ( odomaspelltemple@outlook.com ) and you will give a testimony too wish you Good luck guys...
8
FAITH
Report this comment as inappropriate
Feb 24, 2017 @ 5:17 pm
HELLO everybody am from New Zealand I wanna thank the great DR ABOR for curing me from herpes virus and hiv with the help of his herbal medicine am very happy, I never thought I would ever be cured because of the condition the doctor give to me, until a friend of mine direct me to this man called DR ABOR who healed me totally from herpes virus and hiv, he is a good man and he also cast spell, you can reach him with IRABORSPELLHERBALHOME@GMAIL.COM
and he also cure HEPATITIS A B C
and ANY TYPE OF CANCER, LUPUS, HPV, LOOKING FOR BABY, ERECTION EJACULATION
and HIV AIDS
he also cast spell to get your EX BACK
you can reach him on via IRABORSPELLHERBALHOME@GMAIL.COM
9
Anita Segorp
Report this comment as inappropriate
Feb 24, 2017 @ 7:19 pm
Hi everyone I want to appreciate the great work of Dr Bude, I have been diagnose of herpes infection for a period of 2years, I’ve lose all hope that there is no cure and I have been taken medicine to sustain myself till I got to know about Dr Bude through a friend who he cured of HIV. I contacted him and he sent me a Herbal Medicine which I took as prescribed for some period of 2 weeks and I went to the hospital after taking the Herbal medicine for check up and I was confirmed Herpes Negative after 2 years of being positive, it is indeed a miracle, Dr Bude is a great man, I have heard so much about how he has help lot of people, if you have any issue you can contact him for help. Email:drbudeherbalhome@gmail.com or phone him on +2349035820114. While I was on his medication I understood that he can also cure HERPES, HIV/AIDS,DIABETES, ASEPSIS, CANCER, Male/female menopause, Menstruation problem and many more. Contact him today to get your miraculous cure..
10
Robert Alvin
Report this comment as inappropriate
Feb 25, 2017 @ 12:00 am
Greatest Joy in my life today HIV/AIDS has cure but doctor said HIV Disease has no cure until i met Dr.SABU who help me in my life. I was infected with HIV/AIDS DISEASE in 2012, i went to many hospitals for cure but there was no solution, so I was thinking how can I get a solution,so that my body can be okay.until this faithful day as i was browsing the net I saw a testimony on how Dr.SABU helped people in curing HIV disease, quickly I copied his Email which is drsabuspelltemple@gmail.com so i contacted him for solution for my HIV DISEASE,so Dr.SABU told me that his going to prepare herbal medicine for my health,then he prepared the medicine and luckily after 2week my HIV we be cured.Dr.SABU is well recognize as one of the best herbalist doctor in Africa, you don't have to be sad anymore or share your tears anymore on this disease when the cure have already be found by Dr.SABU herbal medicine,he so cure HPV,CANCER,HERPES,ALS,HEPATITIS B, DIABETIC, ASTHMA,contact him via whatsapp number:+2347057624993.
11
RUTH MARIS
Report this comment as inappropriate
Feb 25, 2017 @ 12:00 am
All thanks to Dr Alli for curing my HERPES SIMPLEX VIRUS / HPV with his herbal medicine, i do not have much to say but with all my life i will for ever be grateful to him and God Almighty for using Dr Alli to reach me when i thought it was all over, today i am happy with my life again after the medical doctor have confirmed my HERPES SIMPLEX VIRUS / HPV of 5 is gone,i have never in my life believed that HERPES SIMPLEX VIRUS could be cured by herbal medicine. so i want to use this means to reach other persons who have this disease by testifying the power of Dr Alli that all hope is not lost yet, try and contact him by any means for any kind of disease with his email: ( allispellhelp1@gmail.com ) or +2348100772528.
12
Susan Morgan
Report this comment as inappropriate
Feb 25, 2017 @ 3:03 am
I have been suffering from (HERPES SIMPLEX VIRUS) disease for the past two years and had constant pain, especially in my knees. During the first year,I had faith in God that i would be healed someday.This disease started circulating all over my body and i have been taking treatment from my doctor, few weeks ago i came on search on the internet if i could get any information concerning the prevention of this disease, on my search i saw a testimony of someone who has been healed from (HERPES SIMPLEX VIRUS) by this Man Dr Ero and she also gave the email address: dreroherbaltreatment@gmail.com of this man and advise we should contact him for any sickness that he would be of help, so i wrote to Dr. Ero telling him about my (HERPES Virus) he told me not to worry that i was going to be cured!! hmm i never believed it,, well after all the procedures and remedy given to me by this man few weeks later i started experiencing changes all over me as the Dr Ero assured me that i have cured,after some time i went to my doctor to confirmed if i have be finally healed behold it was TRUE, So friends my advise is if you have such sickness or any other at all you can email:: dreroherbaltreatment@gmail.com.
13
brittany yate
Report this comment as inappropriate
Feb 25, 2017 @ 12:12 pm
Am really happy that i and my husband are cured of (HERPES SIMPLEX VIRUS) with the herbal medicine of Dr SEBI , i have been suffering from this disease for the past 3 years without solution until i came across his website of this doctors who have cure so many people with his herbal medicine, i also choose to give him a chance to help me and my husband, he told me what to do and i kindly did it, and he gave us his herbal medicine and direct me on how to use it, i also follows his instruction for use and he ask us to go for a check up after 3 weeks and which i did, to my greatest surprise our result came out as negative, we are really happy that there is someone like this DR SEBI who is ready to help anytime any day. to all the readers and viewers that is doubting this testimony stop doubting it and contact this Dr and see if he will not actually help you. i am not a stupid woman that i will come out to the public and start saying what someone have not done for me .contact him now if you are also in need of help via email drsebispelltemple@gmail.com or whatsapp number +2348153863900 may bless you sir for all your good works. contact dr sebi today for your following diseases below

HIV/AIDS

DIABETES

HPV

PENIS ENLARGEMENT
14
roseline
Report this comment as inappropriate
Feb 25, 2017 @ 1:13 pm
i want to tell the world about how i got cured from HIV Disease by Dr. Ozala. i was Infected with HIV Disease for so many years and i was tired of life because of the sufferings i was going through, so one faithful day a friend of mine gave me a contact of a herbal doctor who cured her cousin from HIV Disease and immediately i contacted the Doctor on his email address: (drozalahomeremedy@gmail.com) and his whatsapp: +2349074008745 and immediately the Doctor sent me a herbal medicine and told me to take the medicine only at bed time with is at night and i did and immediately the HIV Virus DISAPPEARED and i was cured from HIV Disease, the name of this Doctor is Dr Ozala.. so if you are infected with HIV Disease or any other dangerous and uncurable Disease then Dr. Ozala is the right man to be contacted for the cure. so kindly contact him now on his email: (drozalahomeremedy@gmail.com) or His Whatsapp number: +2349074008745... once again, Dr. Ozala thank you very much for what you did for me am very grateful... if you know that you are infected with any deadly virus, kindly contact Dr. Ozala and the deadly virus will be gone for ever.
15
Mrs Taneka
Report this comment as inappropriate
Feb 25, 2017 @ 1:13 pm
Hello dear readers, I’m Mrs taneka from Texas United State. Am a single Mother of a lovely daughter. I want to tell the whole world about the good deeds Dr Ofure did for me, I was diagnosed of Chronic Obstructive Pulmonary Disease (COPD) is the most common type of heart disease and cause of heart attacks., I was told by my family doctor, that I have only 8 months to live on planet earth, I was so depressed, I thought about my daughter, I don’t want to leave her behind, i first heard of Dr Ofure curing Chronic Obstructive Pulmonary Disease (COPD) with herbal medication by a friend before seeing Testimonies online and references to his website, I never believe in herbal medicine, I collected his email from the testimony i read online just like mine. when i contacted this herbal doctor via his email, he prepared the herbal medicine and sent it to me via courier service, when i received this herbal medicine, he gave me step by instructions on how to apply it, when i applied it as instructed, i was totally cured of this deadly disease within 16 days, I am now free from the deadly disease, my digestive system is now working perfectly, i no longer feel all the horrible pains. Contact this great herbal doctor via his email drofurehabalhome@gmail.com or you message him on his via whatsApp +2348162868851
16
samanthamiller
Report this comment as inappropriate
Feb 25, 2017 @ 1:13 pm
Herpes is a sexually transmitted virus that primarily infects the mouth and the genitals. It is transmitted by bodily fluids – penetration isn’t required for transmission, oral-oral or oral-genital contact will suffice.I WAS ONCE HERPES SIMPLEX VIRUS patient, I have HSVI genitally and I'm one of the rare cases where I was infected by sexual contact. The person who infected me was unaware that he had it, and he tested negative on a blood test (he probably got it from his mother at birth and never had an outbreak in his life)I'm sure I have HSVI (they did a culture of the fluid from the sores i had during my initial outbreak). So it is possible to contract HSVI by asymptomatic asexual contact, so please people talk about this and prevent anyone else from getting it, I'm kind of going through something. Four years ago my love and I both had an OB and when I got the blood work done it came back negative. We were happy in the relationship so I learned to accept it and never really bothered to get tested again. Now, that we broke up I decided to get tested again. I came back negative for both HSV-1 and HSV-2 (got the news!) and have not had an OB since the initial one four years ago. My ex on the other hand has had a few small outbreaks and never came back positive for HSV-1.Only the help of Dr Odia where able to help me out with is Root and Herbs, if you are having any type of this disease or infection like HIV,CANCER OR ANY disease kindly email doctor Odia for cure:( drodiaherbalistcenter @ gmail . com )
17
helen
Report this comment as inappropriate
Feb 25, 2017 @ 3:15 pm
My problem with herpes has caused me many traumas, especially in my sex life. I was so afraid of infecting my boyfriend, I suffered the embarrassment of visiting dermatologists queries hundreds of times.Unfortunately, they did not find a definitive solution to my problem.
The solution came from the least expected place. By reading in a specialized forum on the subject,mentioned a method for eliminating herpes. Many people had tried, with excellent and quick results.I had nothing to lose so I decided to use this method to eliminate my herpes. spent six weeks using this method and my herpes completely disappeared. I recommend this method to all people who want to eliminate the herpes from their body forever,
contact Alohaherbalhome@gmail.com
18
Anney
Report this comment as inappropriate
Feb 25, 2017 @ 7:19 pm
Hello everyone, I have been infected with HSV 1&2 which I contacted from my partner since 3yrs with a lot of outbreak and different syptoms which almost cost me my life. One day I came across one herbalist online who I contacted through mails and phone calls, but it cost me some money and now I'm cured. A big thanks to God and Dr.Emuan and you can reach him on dremuansolution@gmail.com
19
Ranieri wesie
Report this comment as inappropriate
Feb 26, 2017 @ 3:03 am
God bless Dr. Myron for his marvelous work in my life, I was diagnosed of HERPES/HIV since 2010 and I was taking my medications, I wasn't satisfied i needed to get the HERPES.HIV out of my system, I searched about some possible cure for HERPES/HIV i saw a comment about Dr. Myron, how he cured HERPES/HIV with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine through UPS SPEED POST. I took the medicine as prescribed by him and 8 days later i was cured from HERPES/HIV,thank you drmyronherbaltemple@gmail.com Dr Myron ONCE AGAIN THANK YOU SIR
Dr Myron cure the flowing virus, contact his United state branch +19147094469 add him on whatsapp +2348158836673

1 cancer cure
2 diabetes cure
3 ringing ear
4 herpes cure
5 warts cure
6 HPV cure
7 Hiv
7 get your ex back
8 pregnancy herbal medicine
9 prostate enlargement
20
Ben William
Report this comment as inappropriate
Feb 26, 2017 @ 4:04 am
Hello Every one I am Ben William from New York: I have been suffering from a deadly disease called HERPES for the past 1year and 2months now, and i have spent a lot of money and my time going from one hospital to another seeking for solutions, and going for Constant check up became my hobby, not until last Month, as i was searching through the internet, and i saw a testimony on how DR ADEMUSHI has helped so many sick souls and saved lives in curing different kinds of disease, quickly i copied his email Address which is drademushiherbalhome@hotmail.com and I had a conversation with him and he assure me that he will cure me which i 100% believe him base on the conversation i had with him. He told me that he is going to prepare herbal medicine and have it brought to my door step which he did as he said, then he asked me to go for medical checkup after 3 weeks of taking the herbal medicine, and i did exactly as i was instructed, i went for check up and test was carried out on me, and behold the result came out negative I was tested Herpes Negative and there was no any symptoms of any disease in my body again. I couldn't believe my eyes that i was free from the deadly disease, I am so happy now and i will forever remain thankful and grateful to Dr ADEMUSHI for making me live my normal life again, Dr ADEMUSHI has only asked me to show appreciation and ask me to share my story and testimony to the whole world, faithfully am doing it now, please brothers and sisters this man is indeed a great man and his cure is 100% permanent i owe him a lot in my life. If you are having a similar problems just email him on drademushiherbalhome@hotmail.com you can also call or whatsapp him on:+2348131652960. and have your problems solve once and for all. He also said that with herbs he can cure any kind of sickness no matter the condition. Give him a trial now and share your testimony.
21
joyce mary
Report this comment as inappropriate
Feb 26, 2017 @ 4:04 am
My name is JOYCE MARY, and I base in USA...My life is back!!! I really happy that i and my husband are cured of (HERPES SIMPLEX VIRUS) with the herbal medicine of Dr Odioa , i have been suffering from this disease for the past 3 years without solution until i came across the email of this doctors who have cure so many people with his herbal medicine, i also choose to give him a chance to help me and my husband, he told me what to do and i kindly did it, and he gave us his herbal medicine and direct me on how to use it, i also follows his instruction for use and he ask us to go for a check up after 3 weeks and which i did, to my greatest surprise our result came out as negative, we are really happy that there is someone like this DR who is ready to help anytime any day. to all the readers and viewers that is doubting this testimony stop doubting it and contact this Dr and see if he will not actually help you. i am not a stupid woman that i will come out to the public and start saying what someone have not done for me. His contact on: odioaherbalcurehome@gmail.com or call on +2347059055577
22
Clifford Jones
Report this comment as inappropriate
Feb 26, 2017 @ 5:05 am
Well done sir. for helping millions of people around the globe to know that you are there to save them. I'm also very grateful to have met you. when i have suffered Diabetes type 2 for more than 8years and also visited several places and finally found you are the very stage of giving up. i will appreciate when i some people testify of how you have cure theirs HIV aids. Herpes disease. Hepatitis B. High blood pressure. arthritis. brain disease. multiple sclerosis and so on. when i went through all this different testimony. and i knew i was at my final place to be cured and when i emailed him on his email:drokususolutiontemple@gmail.com and he wrote back after so few minutes. telling me i will suffer no more once i get his medicine and use it. i will see the wonderful work of his herbal herbs. i beckoned on his words and gave him what he needed to prepare my cure and he sent to me and told me how to take it and should go and test my self after the last day. which i did and my result was very overwhelming. if there is so many herbal doctors are out there like Dr Okusu. the world will be in a better hand. contact him today if you need help like i did. on his Mobile:+2349037835860 or his email:drokususolutiontemple@gmail.com
23
sonia
Report this comment as inappropriate
Feb 26, 2017 @ 8:08 am
HERPES CURE...THIS IS REAL ! TAKE TIME TO READ

TESTIMONY OF HOW I GOT CURED FROM GENITAL HERPES SIMPLEX VIRUS WITHIN 14DAYS[with Herbal Traditional medicine]

Hello Everyone out there,I am here to give my testimony about a Herbalist called Dr IDUMEBO, who helped me in my life. I was infected with HERPES SIMPLEX VIRUS 2 in 2015, i went to many hospitals for cure but there was no solution, so I was thinking how can I get a solution out so that my body can be okay. One day I was in the river side thinking where I can go to get solution. so a lady walked to me telling me why am I so sad and i open up all to her telling her my problem, she told me that she can help me out, she introduce me to a doctor who uses herbal medication to cure HERPES SIMPLEX VIRUS 2 and gave me his email, so i mail him. He told me all the things I need to do and also give me instructions to take, which I followed properly. Before I knew what is happening after two weeks the HERPES SIMPLEX VIRUS that was in my body got vanished . so if you are also heart broken and also need a help, you can also email him via;
dridumeboherbalhome@gmail.com OR dridumeboherbalhome@gmail.com

He also have a herbal cure for HIV.

Comment about this article, ask questions, or add new information about this topic:

CAPTCHA