Cold sore



Definition

Cold sores are small red blisters, filled with clear fluid, that form on the lip and around the mouth. Rarely, they form on the roof of the mouth. Cold sores are caused by the herpes simplex virus type 1 (HSV-1), which lives inside nerve tissue. Despite their name, cold sores have nothing to do with colds. The herpes simplex virus type 1 should not be confused with the herpes simplex virus type 2 (HSV-2), which most often causes genital herpes.

Description

There are eight different kinds of human herpes viruses. Only two of these, herpes simplex types 1 and 2, can cause cold sores. It is commonly believed that herpes simplex virus type 1 infects above the waist and herpes simplex virus type 2 infects below the waist. This is not true. Both herpes virus type 1 and type 2 can cause herpes lesions on the lips or genitals, but recurrent cold sores are almost always type 1.

The sores can appear within days or weeks or even years following the first exposure to the virus. The first time symptoms appear they are usually more intense than later outbreaks. For example, some children experience more pain at the blister site or even flu-like symptoms, including swollen glands, fever , or sore throat . Medical names for cold sores include oral herpes, labial herpes, herpes labialis, and herpes febrilis.

Transmission

Herpes simplex virus is transmitted by infected body fluids (such as saliva) when they contact breaks in another person's skin or mucous membranes. Newborns may become infected during delivery through an infected birth canal. HSV-1 can be passed to children by parents, nurses, and caregivers who fail to practice careful hand washing. Children with burns , eczema, or diaper rash or those who are immunosuppressed are highly susceptible to the herpes virus.

VIRUS VERSUS BACTERIA Viruses behave differently than bacteria. While bacteria are independent and can reproduce on their own, viruses enter human cells and force them to make more viruses. The infected human cell dies and releases thousands of new viruses. The cell death and resulting tissue damage causes the cold sores. In addition, the herpes virus can infect a cell, and instead of making the cell produce new viruses, it hides inside the cell and waits. The herpes virus hides in the nervous system. This action is called latency. A latent virus can wait inside the nervous system for days, months, or even years. At some future time, the virus "awakens" and causes the cell to produce thousands of new viruses that cause an active infection.

Latent and active infection is understood by considering the cold sore cycle. The first infection is the primary infection. The primary infection is controlled by the body's immune system and the sores heal. Between active infections, the virus is latent. At some point in the future, latent viruses become activated and once again cause sores or recurrent infections. Although it is unknown what triggers latent virus to activate, several conditions bring on infections. These include stress, illness, fever, fatigue, exposure to sunlight, menstruation , and diet.

Demographics

The herpes simplex virus is widespread in children. Thirty-five percent of five-year olds carry HSV-1 antibodies. A primary infection commonly occurs by the time a child reaches age five. These viral infections are more common in lower socioeconomic groups.

Nearly 80 percent of the general population carry the herpes simplex virus that causes cold sores, and 60 million have outbreaks once or more in a year. Most infants and children harbor the herpes virus before age ten. Interestingly enough, only 20 percent to 25 percent of those carrying the virus ever gets symptoms (break out in cold sores).

Causes and symptoms

While anyone can have the herpes virus infection, not everyone will show symptoms. The first symptoms of herpes occur within two to 20 days after contact with an infected person. Symptoms of the primary infection are usually more severe than those of recurrent infections. The primary infection can cause symptoms like other viral infections, including fatigue, headache , fever, and swollen lymph nodes in the neck.

Typically, 50 to 80 percent of children with oral herpes experience a prodrome (symptoms of oncoming disease) of pain, burning, itching , or tingling at the site where blisters will form. This prodrome stage may last a few hours or one to two days. The herpes infection prodrome occurs in both the primary infection and recurrent infections.

In 95 percent of the patients with cold sores, the blisters occur at the outer edge of the lips, which is called the vermillion border. Less often, blisters form on the nose, chin, or cheek. Following the prodrome, the disease process is rapid. First, small red bumps appear. These quickly form fluid-filled blisters.

Causes of cold sores in children

Infants are most likely to get a cold sore because someone with an active virus kisses them. The cause can even be a kiss from someone who did not have a visible sore but had the virus in his or her saliva. A baby may also get the herpes virus passing through the birth canal if the mother has genital herpes.

Once a child gets the virus, it stays in his body permanently, hiding in nerve cells near the ear. In some children, the virus lies dormant and never causes harm. In others, it periodically wakes up and triggers cold sores. Nobody knows what stirs the virus into action, but stress, fever, colds, and sunburn encourage outbreaks. Rich foods such as chocolate, food allergies , or hormonal changes may also cause outbreaks in children and adolescents.

Symptoms of cold sores in infants

The first symptoms of cold sores in infants are swollen gums and sore mouth. A few days later, there is a cluster of small blisters on or near the lips that turn into a shallow, painful sore. The breakout is often accompanied with fever and swollen lymph glands in the neck. In a few days the sore will crust and slowly disappear. The whole flare-up lasts about seven to ten days. The next time the infant has an outbreak the blister is the first symptom, not the swollen gums and painful mouth. If not treated, recurring outbreaks may last longer.

Stages of cold sores in children and adolescents

Cold sores, untreated, can last up to 14 days. Children often feel the tingling at the site before the sore appears. Parents should begin the treatment at the first sign of tingling or redness, which can reduce the time to two to four days. Beginning treatment after the blister appears can also significantly reduce the time and degree of pain. The following describes the stages of a cold sore:

  • Day 1: Prodrome (tingle) stage: Before a blister appears, the child usually feels a tingling, itching, or burning sensation beneath the skin, usually around the mouth or the base of the nose. This is the best time to start treatment.
  • Days 2 to 3: The blister or blisters appear. Children usually have one or several blisters on or around the moth, most often at the border of the lip and the skin on the face. Cold sores occasionally occur on the roof of the mouth.
  • Day 4: Ulcer or weeping stage: The blister opens, revealing a reddish area. The child is most contagious and in the most pain at this point.
  • Days 5 to 8: Crusting stage: The blisters dry up, and a crust forms which is yellow or brown in color. Children should be told not to pick at this crust.
  • Days 9 to 14: Healing stage: A series of scabs form over the sore, each smaller than the previous one until the cold sore is healed.

When to call the doctor

The HSV-1 virus can cause ocular herpes, a serious eye infection affecting the cornea (the clear window) of the eye, which can threaten vision and needs immediate medical attention and treatment. When a baby or child has a cold sore, parents should do all they can to keep them from touching their eyes. If a painful sore appears on the child's eyelid, eye surface, or on the end of his nose, call the pediatrician right away. The child may need antiviral drugs to keep the infection from scarring the cornea. Ocular herpes can weaken vision and even cause blindness.

Some children have a serious primary (first episode) herpes infection called gingivostomatitis, which causes fever, swollen lymph glands, and several blisters inside the mouth and on the lips and tongue that may form large, open sores. These painful sores may last up to three weeks and can make eating and drinking difficult. Because of this problem, young children with gingivostomatitis are at risk for dehydration . Children with this condition should be seen by a doctor.

Most infants have protection for at least six months from HSV-1 by antibodies they received from their mothers. But if a newborn gets a cold sore, the pediatrician should be called right away.

If the immune system of children is compromised because of cancer treatment or AIDS , they could have more serious problems with the herpes virus. Parents should let the doctor know if these health conditions exist.

Children with a history of frequent herpes flare-ups who spend time skiing or on the beach should call a doctor for a prescription for starting oral anti-herpes medication (pills) before such outings and then using sunscreen while they are outside. These precautions can prevent most outbreaks.

Diagnosis

Cold sores are diagnosed by review of symptoms, physical examination, and history. The diagnosis is confirmed by various viral tests. A Tzanck or Papanicolau smear may be done. A positive smear cannot distinguish between varicella zoster virus and HSV-1, and a negative smear does not rule out HSV infection. Tissue culture provides a more reliable method of diagnosis. Cells killed by the herpes virus have a certain appearance under the microscope. Laboratory blood test looks for the virus or to confirm the presence of antibodies that fight the virus.

Approximately 85 percent of active herpes infections are without symptoms. When the symptoms do appear, they have the following sequence:

  • burning, itching, or tingling at the site before the sore appears
  • clusters of fluid-filled vesicles ulcerate, dry, and crust
  • lesions dry and crust within seven to ten days
  • usually one or two lesions present on the lips, tongue, gingival, or buccal mucosa
  • puritis (itching) and pain

Treatment

There is no cure for herpes virus infections. Antiviral drugs are available that have some effect on lessening the symptoms and decreasing the length of herpes outbreaks. There is evidence that some may also prevent future outbreaks. These antiviral drugs work by interfering with the reproduction of the viruses and are most effective when taken as early in the infection as possible. For the best results, drug treatment should begin during the prodrome stage before blisters are visible. Depending on the length of the outbreak, drug treatment could continue for up to ten days.

Antiviral pills such as acyclovir (Zovirax), famciclovir, (Famvir), and valacyclovir (Valtrex) can cancel an outbreak and help prevent recurrent outbreaks. Acyclovir (Zovirax) is the drug of choice for herpes infection and can be given intravenously or taken by mouth. A liquid form for children is also available. Acyclovir is effective in treating both the primary infection and recurrent outbreaks. When taken by mouth, acyclovir reduces the frequency of herpes outbreaks.

Antiviral creams Zovirax and Denavir should be applied within the first 24 hours of feeling the tingling or discomfort, before the plaster erupts. The duration of the outbreak can be shortened by a day or two. Antiviral creams are not as effective as the pills.

During an outbreak, sores should be washed once or twice a day with warm, soapy water, and gently patted dry. Over-the-counter lip products that contain the chemical phenol (such as Blistex Medicated Lip Ointment) and numbing ointments (Anbesol) help to relieve cold sores. A bandage over the sores protects them and prevents spreading the virus to other sites on the lips or face.

Close-up view of a cold sore, caused by herpes simplex virus, on a patients mouth. ( Kenneth Greer/Visuals Unlimited.)
Close-up view of a cold sore, caused by herpes simplex virus, on a patient's mouth.
(© Kenneth Greer/Visuals Unlimited.)

Acetaminophen (Tylenol) or ibuprofen (Motrin, Advil) may be necessary to reduce pain and fever.

Alternative treatment

Cold sores in infants and children will go away on their own, but there are measures that will help the child feel better:

  • To ease the pain, apply ice to the sore, or if the doctor approves, give the baby a mild pain reliever, such as ibuprofen or acetaminophen. (Do not give aspirin to a baby; it could trigger Reye's syndrome. This is a rare but potentially life-threatening illness.) Choices for pain relief include medication, ointments, or mouth rinses recommended by the pediatrician. Parents may also use Oragel, an ointment often used for canker sores or teething.
  • Avoid giving the child spicy, salty, or sour foods, and foods with acid (oranges and grapefruits), which can irritate the open sore.
  • Apply a water-based zinc ointment such as Desitin. It helps dry out the sore so it can heal faster.
  • Extra sleep and plenty of liquids to drink can help.

Adolescents can learn to manage their own outbreaks. They can take the following steps:

  • Use over-the-counter pain relievers, such as acetaminophen (Tylenol) or ibuprofen (Motrin, Advil).
  • Avoid squeezing or picking the blister.
  • Apply ice to ease the pain.
  • Acidophilus pills may be helpful in treating cold sores. L-lysine is an amino acid widely advertised to treat cold sores. Conflicting medical opinions exist about its effectiveness.

Nutritional concerns

If children are prone to recurrent viral infections, parents should review their eating habits. The children should avoid foods and drinks that are proven suppressors of immunity (foods high in sugar, caffeine , and alcohol content) and have regular meals with plenty of fresh vegetables and fruits and whole-grain products. Some foods may be increased or reduced for specific types of viral infections. For herpes, foods containing the amino acid arginine (nuts and seeds) need to be reduced, and those containing the amino acid lysine (yogurt and cottage cheese) need to be increased. Immune system health in children can also benefit from a wide range of vitamins and minerals as nutritional supplements. Vitamin B complex and vitamins A, C, and E are the most important supplements.

Prognosis

Anyone can become infected with the herpes virus. Once infected, the virus remains latent in the body for life. It lives in nerve cells where the immune system cannot find it. The herpes virus lies dormant in the nerves of the face and is reactivated by sunburn, a recent viral illness (cold or flu), and periods of stress. Cold sores spread from person to person by direct skin-to-skin contact.

The highest risk for spreading the virus is the time period beginning with the blisters and ending with scab formation. However, infected people need not have visible blisters to spread the infection since the virus may be present in the saliva without obvious oral lesions.

Most children experience fewer than two recurrent outbreaks of cold sores each year; some have frequent outbreaks and others never experience outbreaks. Most blisters form in the same area each time and are triggered by the same reasons (such as stress, sun exposure, etc.).

Prevention

Cold sores are contagious. As of 2004 there were no herpes vaccines available, although herpes vaccines were in research and development. Avoiding close contact with people shedding the virus is the best way to prevent primary herpes. Several practices can reduce reoccurring cold sores and the spread of virus:

  • Parents should teach children not to share drinks, food, or eating utensils, and not to exchange kisses with someone with mouth sores.
  • When parents have an outbreak, they should avoid kissing their children (and other adults).
  • Parents should be watchful of infected children and not allow them to share toys that may be put into the mouth. Toys that have been in the child's mouth should be disinfected before other children play with them.
  • Parents should be especially careful with infants; they should not kiss the eyes or lips of a baby who is under six months old. The child's eyes and genitals are particularly susceptible to the herpes virus. They should keep the child from picking at a cold sore as much as possible.
  • To keep from spreading the infection to other parts of the child's body or giving the virus to someone else, parents and caregivers should wash their hands and the child's hands often, especially after feedings and diaper changes.
  • The child should be protected from the sun, since exposure to sunlight can trigger an outbreak. If the child is outside on a sunny day, generously apply sunscreen and lip balm that contains sun block before prolonged exposure to the sun. Sun block should be used during both winter and summer months, to help prevent cold cores. Wearing a hat with a large brim is also helpful.
  • Parents should wear gloves when applying ointment to a child's sore. They should remove gloves and wash hands before and after changing diapers.
  • Antibiotic ointments may be used to treat secondary bacterial infection of lesions. Parent should avoid using steroid creams or gels on a suspected herpes infection because these agents could make the infection worse.
  • Parents should maintain good general health. A healthy diet, plenty of sleep, and exercise help to minimize the chance of getting a cold or the flu, which may bring on cold sores. Also, good general health keeps the immune system strong; this helps to keep the virus in check and prevents outbreaks.

Parental concerns

The child with a herpes infection is usually miserable and needs generous cuddling and comfort in spite of the infection. Parents of children who get cold sores should be aware of early symptoms and be ready to treat the sore in the first couple days. They should also keep in mind the prevention tips mentioned above. Parents should call the child's pediatrician if the child has not had a cold sore before, especially in the case of babies.

KEY TERMS

Antiviral drug —A medication that can destroy viruses and help treat illnesses caused by them.

Contagious —The movement of disease between people. All contagious disease is infectious, but not all infections are contagious.

Herpetic gingivostomatitis —A severe oral infection that affects children under five years of age; vesicles and ulcerations, edematous throat, enlarged painful cervical lymph nodes occur; chills, fever, malaise, bed breath, and drooling.

Latent virus —A nonactive virus that is in a dormant state within a cell. The herpes virus is latent in the nervous system.

Oral lesions —A single infected sore in the skin around the mouth or mucus membrane inside of the oral cavity.

Prodrome —Early symptoms that warn of the beginning of disease. For example, the herpes prodrome consists of pain, burning, tingling, or itching at a site before blisters are visible while the migraine prodrome consists of visual disturbances.

Recurrence —The return of an active infection following a period of latency.

Reye's syndrome —A serious, life-threatening illness in children, usually developing after a bout of flu or chickenpox, and often associated with the use of aspirin. Symptoms include uncontrollable vomiting, often with lethargy, memory loss, disorientation, or delirium. Swelling of the brain may cause seizures, coma, and in severe cases, death.

Secretion —A substance, such as saliva or mucus, that is produced and given off by a cell or a gland.

Resources

BOOKS

Health and Healing the Natural Way: Energize Your Life. Pleasantville, New York: The Reader's Digest Association, Inc., 2000.

Parker, Philip M., et al. Cold Sores: A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References. Boulder, CO: netLibrary, 2003.

PERIODICALS

Novatnack, Ellen, and Steven Shchweon. "Herpes: A bigger problem than you think." RNMagazine 65 (June 2002):31-37.

WEB SITES

"Herpes labialis (oral Herpes simplex)." MedlinePlus , July 12, 2004. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000606.htm (accessed December 14, 2004).

Aliene S. Linwood, RN, DPA, FACHE Belinda Rowland, PhD



User Contributions:

1
hannah xuereb
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Jul 29, 2006 @ 11:11 am
my daughter is 15 months old she had coldsores come up about 3 months ago and ended up in hospital she evently got better. They have come up again been to the doctors they gave her zarvirax its been about a week her temp has gone as high as 40.2 keep giving her fluids as she is not eating i am worried as she is small for her age anyway do u have any suggestions?
2
Dawn
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May 6, 2008 @ 8:20 pm
My 4 1/2 year old son has recently complained of his mouth hurting, yet there was nothing visually there. The day care provider called and informed me that he has a "cold sore". Now, i don't know anyone that has a cold sore at this time, and he has not been around kissing anyone that i am aware of. I was just wondering if cold sores can be inherited?? I only ask this because my son's father has a history of cold sore/ canker sore breakouts and want to know if i have to be prepared for my son to have them as well.
3
Jane Diamond
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Sep 23, 2016 @ 7:07 am
I am surprised and still shocked with the great miracle that happened in our family, my husband and I have been to various hospitals and I have been tested HIV positive this year in June and my husband was HIV negative I was so surprised because i was still ill at that time and that lead us to the hospital, but the doctor confirmed that he had kidney/ Cancer problems. since we spent money around to get drugs from different hospital, I was looking through the internet for help when I saw a comment of people talking about how Dr uwa on how he heal them of HIV disease and other diseases, I did not believe at first but I just choose to try the herbs and I contacted him by email address he told me what to do even if mine was more stressful than my husband different herbs was sent to us. To my surprise, my husband and I waited patiently for the treatment and the instruction given to us by this man called Dr uwa and we went for a medical test after 2 weeks and the result was negative and my husband reconfirmed and it was quite correct, even our doctor was confused he said he has never seen this kind of miracle before. Dr uwa thank you very much for the good work in our lives and God will bless you for the good work you did. you can also contact that great and powerful man, if you have a problem with
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4
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Sep 24, 2016 @ 2:02 am
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5
Laura Andrew
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Sep 24, 2016 @ 4:04 am
My name is Laura I live in united state, i am here to give my testimony about a spell caster called Priest Ola who helped me in my life. I was infected with HERPES SIMPLEX VIRUS in 2014, i went to many hospitals for cure but there was no solution, so I was thinking how can I get a solution out so that my body can be okay.So One day I went online on the internet to know more clue about the Herpes Simplex Virus i came across a review of a lady called Helen saying that she got her Herpes Simplex Virus cured by A spell caster Called Priest Ola. And she also went as far to drop an email address and website address including Priest Ola telephone number and advise anyone to contact Priest Ola for any kind of help. So i gave a try by contacting him through his website and explain my problem to him. He told me all the things I need to do and also give me instructions to take, which I followed properly. Before I knew what is happening after two weeks the HERPES SIMPLEX VIRUS that was in my body got vanished . so if you are also heart broken by any deadly diseases like HERPES HIV, shingles,low sperm count or bringing back your ex lover, this great man is extremely the best in which I have seen and applauds and if you also need a help, you can also email him via email successhealinghome@outlook.com. You can also call his telephone number +1 415 941 5072. GOOD LUCK TO YOU ALSO.
6
Susan Morgan
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Sep 24, 2016 @ 8:08 am
Hi Friends i am so glad to write this article today to tell the world how Dr Ekpiku cured my HSV VIRUS,i have been detected with HSV-1 AND HSV-2 since five years ago, ever since then my life has been in complete bizarre and agony,i have used so many drugs that was prescribed to me by several doctors,but it didn't cure my HSV VIRUS neither did it reduce the pain,until a certain i was checking for solution in the internet,then miraculously came across Dr Ekpiku the powerful herbalist that cure numerous individuals HSV-1 AND HSV-2 INFECTION,then i contacted his email: ekpikuspellhomeofgrace@gmail.com i explained everything to him and prepared a cure that cure my HSV-1 AND HSV-2 disease totally after receiving his herbal medicine, so my friends viewers why wait and be suffer when there is someone like Dr Ekpiku that can cure any disease HIV/ CANCER/ HEPATITIS B VIRUS, you can contact his via: ekpikuspellhomeofgrace@hotmail.com or whatapps, call +2348073673757.
7
jane clinton
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Sep 24, 2016 @ 6:18 pm
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8
portia petterson
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Sep 25, 2016 @ 3:03 am
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9
steven ashely
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Sep 25, 2016 @ 6:06 am
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10
Felix Clark
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Sep 25, 2016 @ 9:09 am
Hello viewers..i don't just know the reason why some people are still finding it difficult to believe that there is no cure for Herpes virus i have been Herpes since last six years,and my doctor say there is no cure for herpes and anyone that will say herbal medicine can cure herpes is lies,then discus with a friend of mine who was once troubled with herpes disease,he told me it a lie that herbal medicine exist, that Dr.Suku cured him,thereafter he referred to a doctor called Dr.Suku and told me to contact him,so i contacted Dr Suku lo and behold after 2 weeks my herpes virus was cured totally am now herpes negative by Dr.Suku Herbal medicine,so i no that there is some people that can't still believe that herpes have no cure so friends i will not lie to you Dr.Suku is a great herbalist that cure any types of Disease,HERPES.HIV/AIDS.CaANCER.HEPATITIS B.LOW SPERM CAM.DIABETICS.
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11
mandy
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Sep 25, 2016 @ 3:15 pm
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12
kalu
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Sep 25, 2016 @ 3:15 pm
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in a different hospital and again they confirmed me Hepatitis b negative. Even
my medical doctor was confused, he said he has never seen this kind of a
miracle before. I really want to thank DR.Sabuta for saving my life, I
never believed that I will be Hepartitis b negative today, I am grateful Sir. If
you are having any disease like HIV, DIABETES, herpatitis b, HERPES or any illness please
contact him now through his email: (drsabutahealinghome@gmail.com).
13
anna
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Sep 25, 2016 @ 3:15 pm
Hello Everyone, my names is Anna Brenda, i am from Florida USA. I want to share my testimonies to the general public on how this great man called Dr goodnews who cure my herpes. I have been a HERPES patient for over 9 Months and i have been in pains until i came across this lady when i traveled to Africa for Business trip and she told me that there is this great herbal doctor that help her to cure her herpes and she gave me his email address for me to contact and i did as she instructed. The man Dr goodnews told me how much to buy the herpes herbal medication and how i will get it, which i did. And to my greatest surprise that i took the Herpes herbal medicine for just two week as he instructed and behold i went for a herpes test, to my greatest surprise for the doctor confirmed me to be herpes free and said that i no longer have herpes in my system and till now i have never felt any pains nor herpes again, so i said i must testify the goodness of this man to the general public. So if you are there surfing from this Herpes problems or any deadly disease or other disease for i will advice you to contact him on his working email: drgoodnewstemple@gmail.com and i assure you that he will help you just as he did for me okay.contact him on his email: drgoodnewstemple@gmail.com
THESE ARE THE THINGS Dr Goodnews DOES
1. HERPES
2. CORONARY HERT DISEASE
3. HIV/AIDS
4. CANCER and any other diseases
14
frank
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Sep 25, 2016 @ 3:15 pm
Hello Everyone, my names is frank wilson, i am from Florida USA. I want to share my testimony to the general public on how this great man called Dr sabuta who cured my cancer. I have been a cancer patient for over 7 Months and i have been in pains until i came across this lady when i traveled to milan for Business trip who was once a cancer patient, i explained every thing to her and she told me that there is this Great Dr that help her to cure her cancer and she gave me his email address for me to contact and i did as she instructed. And the man Dr sabuta told me what to do and how i will get the herbal medication which i did. And to my greatest surprise that i took the herbal medicine for just three week and behold i went for a test, for to my greatest surprise the Doctor confirmed me to cancer free and said that i no longer have cancer and till now i have never felt any pains again, so i said i must testify the goodness of this man to the general public for if you are there suffering from this cancer problems or any deadly disease or other disease for i will advice you to contact him on his working email: (drsabutahealinghome@gmail.com) and i assure you that he will help you just as he did for me okay
contact him on his email: drsabutahealinghome@gmail.com
THESE ARE DISEASES THAT DR. SABUTA CAN CURE
1. HERPES
2. LASSA FEVER
3. GONORRHEA
4. HIV/AIDS
5. LOW SPERM COUNT
6. MENOPAUSE DISEASE
7. EPILEPSY
8. ASEPSIS
9. CANCER
10. ANXIETY(MENTAL BREAK DOWN)
15
jane clinton
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Sep 25, 2016 @ 4:16 pm
All thanks to Dr okosnu for curing my genital warts, i do not have much to say but with all my life i will for ever be grateful to him and God Almighty for using Dr okosun to reach me when i thought it is all over, today am happy with my two kids and my husband after the medical doctor have confirmed my HIV status Negative,i have never in my life believed that warts could be cure by any herbal medicine. so i want to use this means to reach other persons who have this disease by testifying the wonderful herbs and power of Dr Okosun that all is not lost yet, try and contact him by any means with his email : Doctorokosunspelltemple@gmail.com or call him on +2349059843999 or his whatsapp number +2348107584479
16
wilson paul
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Sep 25, 2016 @ 5:17 pm
DR OBOITE herbal medicine is a good remedy for herpes simplex virus cure.
My name is Wilson Paul, am from UK,I am here to give my testimony about DR OBOITE who helped me in my life, i want to inform the public how i was cured from (HERPES SIMPLEX VIRUS) by DR OBOITE, i visited different hospital but they gave me list of drugs like Familiar, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on HERPES and i saw comment of people talking about how DR OBOITE cured them, when i contacted him he gave me hope and send a Herbal medicine to me that i took and it seriously worked for me, am a free person now without any problem, my HERPES result came out negative, I pray to God to never let me and my family forget you in our life,am now cured permanently, you can also get your self cured my friends if you really need this doctor help, you can reach him now email: droboiteherbalcurehome@gmail.com or call him +2348054265852
17
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Sep 26, 2016 @ 4:04 am
Greetings to the general public my name is Amanda Nancy, i want to inform the public how i was cured of HERPES Simplex Virus by a Doctor called Ojoku Onoss. i visited different hospital but they gave
me list of drugs like Famvir, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on HERPES and i saw
comment of people talking about how Dr Ojoku Onoss cured them. I Was scared because i never believed in the Internet but i was convince to give him a try because i was having no hope of been cured of
HERPES so i decided to contact him on his email that was listed on the comment (ojokuonosshelphome@hotmail.com ) i searched his email on net and i saw a lot of people testifying about his goodness.
when great man. Am so happy, you can also contact him if you have any problem Email (ojokuonosshelphome@hotmail.com OR CALL HIM ON +2348119886007 or whatAspp him on +2348056377915.
18
Wanda Dancy
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Sep 26, 2016 @ 12:12 pm
hello friends I am Wanda dancy from U S A. God is be really good to me in my life,, before people said there is no cure on HIV AIDS, but today many people have now believe that there is a cure for HIV AIDS it can be cured through Africans root and herbs, our great doctors have finally found the cure of HIV AIDS, many have get cured with the help of a great herbal doctor known as Dr uwa he's the one of the great spell herbal doctor in Africa and he has the cure on this disease H.P.V/TYPE 1 TYPE 2 TYPE 3 AND TYPE 4. TYPE 5, human papilomavirus, genital warts, herpes, syphilis, cancer, hepatitis a b and c. high blood pressures, body disease, diabetics, epilepsy, HIV aids, pregnancy,ALS and many difference kinds of diseases, last month he share is Herbal medicine in some medical hospital and now he is well recognize as one of the best spell caster in Africa, you don't have to be sad any more or share your tears any more on this disease when the cure have already be found. in 2015 the total number of people living with HIV was 5.8 million but today the total number is now 2.0 million, if you want to get in touch with him contact him on this e-mail below: druwaherbalcenter@gmail.com cell phone contact +2349052627511 his whatsapp contact is +2348063930531. so now contact him and get rid of your disease. immediately because this disease are not melt for us, with GOD all things are possible, so GOD has use this great dr uwa of dr uwa herbal center to let people no that this disease are not actually melt for us. and also here is my email address you can get in contact with me if you wish to no more about this great wonderful herbal doctor that has so much made me believe in him ok, so here is my email address wandadancy1@gmail.com thanks everybody and most especially you dr uwa of druwaherbalcenter@gmail.com
19
carolina
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Sep 26, 2016 @ 1:13 pm
Take your time and read this testimony do not ignore save others life by ready and sharing this testimony.
This is real take it serious, my name is (CAROLINA) from ENGLAND, who will believe that a herb can cure HIV&AIDS i never believe that this will work i have spend a lot of $$money when getting drugs from the hospital to keep me healthy, what i was waiting for is death because i was broke, one day i heard about this great man who is well know as herbal medical man who has herbs to cure HIV&AIDS and CANCER also, i decided to email him, unknowingly to me that this will be the end of HIV&AIDS in my body, he prepare the herbs for me, and give me instruction on how to take it, at the end of one month when taking the herbs, he told me to go to the hospital for a check up, and i went, surprisingly after the test the doctor confirm me negative i was so so shock i did not believe it was true, i thought it was a joke, i went to other hospital and was also negative, then i took my friend who was also suffering from CANCER to the herbal man. his name is Dr.okosodo., after she has taking the herbs she was also confirm disease free . He also have the herb to cure.
(1) CANCER,
(2) ASTHMA,
(3) HIV&AIDS,
(4) URINARY TRACT INFECTION,
(5) IMPOTENCE,
(6) BARENESS/INFERTILITY
(7) DIARRHEA
(8) DIABETES...E.T.C
please i want every one with this virus to be free and be cured, that is why am dropping his email address. Email: DR OKOSODOPOWERFULHOME@GMAIL.COM call or what-sapp him on +2348136623427 do not hesitate to email him, he is a good and a great man. DR.OKOSODO thank you for saving my life, and I promise I will always and forever testify for your good work
20
wilson paul
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Sep 27, 2016 @ 1:01 am
DR OBOITE herbal medicine is a good remedy for herpes simplex virus cure.
My name is Wilson Paul, am from UK,I am here to give my testimony about DR OBOITE who helped me in my life, i want to inform the public how i was cured from (HERPES SIMPLEX VIRUS) by DR OBOITE, i visited different hospital but they gave me list of drugs like Familiar, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on HERPES and i saw comment of people talking about how DR OBOITE cured them, when i contacted him he gave me hope and send a Herbal medicine to me that i took and it seriously worked for me, am a free person now without any problem, my HERPES result came out negative, I pray to God to never let me and my family forget you in our life,am now cured permanently, you can also get your self cured my friends if you really need this doctor help, you can reach him now email: droboiteherbalcurehome@gmail.com or call him +2348054265852
21
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Sep 27, 2016 @ 2:02 am
A GREAT THANKS TO DR.ALABI FOR CURING ME FROM GENITAL HERPES I AM SO HAPPY TO GIVE THIS TESTIMONY ARE YOU SUFFERING FROM THIS SICKNESS HERE IS DR WHO CAN HELP i am MADUNA MORGAN, was diagnosed with HERPES. i was on riluzole just before i came across Dr Andrey email on the Internet where he cured someone from HERPES,i contacted him and told him about everything. how i am going through pains but to my greatest surprise,Dr Alabi prepare me a cure using natural root and herbs then sent it it through the courier service. with just few days of taking it,my arms,legs came alive. in two weeks of taking his herbal cure i became free from HERPES after a medical test.thanks to Dr Alabi for curing me from HERPES using herbal remedy,kindly email him via;( dralabispelltemple@gmail.com ) or ( dralabispelltemple@yahoo.com ) or ( dralabispelltemple@hotmail.com ) or if you need the Dr help you we whatsapp him number +2348146226679 or call +2348105074556
22
Maria Lucas
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Sep 27, 2016 @ 2:02 am
Herpes Virus is a terrible virus, if not for my Husband and the help of the great Dr. Ehi my life would have been a mess! I was diagnose with Herpes virus in 2005, my husband encouraged me, and told me not to lose hope, I manage to give birth to a baby Boy who was free from this virus, and my Husband was always there for me! One day he came to me and told me that he have found a man who can cure me. Base on scientist, they said there is no cure for Herpes virus; he told me that he has seen many testimonies about him on the internet. We decided to contact him, we filled his Herbal home form, and he asked us to buy some local root and herbs items which we did! and he prepared for me a herbal medicine and 14 days later he asked me to go for medical test, faithfully hopefully i went for the medical test, and Behold, I was cured, from this virus and its was not found in my Body system again... My Dear Husband and my Father Dr. Ehi, God will surely bless the both of you, till the end of time, in Jesus name.. If you have any problem kindly contact Dr Ehi on ( shomorikaspelltemple@yahoo.com) or call him on +2349038669448
23
Jennifer Alexander
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Sep 27, 2016 @ 5:17 pm
My name is Jennifer Alexander From USA texas, Dr OJUGO is the only Dr who
could ever get my HIV-AIDS cured with his healing spell, i have tried
almost everything but i couldn’t find any solution on my disease,
despite all these happening to me, i always spend a lot to buy HIV drugs
from hospital and taking some several medications but no relieve,until
one day i was just browsing on the internet when I come across a great
post of !Nicole! who truly said that she was been diagnose with
HIV and was healed that very week through the help of these great
powerful healing spell doctor, sometime i really wonder why people
called him Dr OJUGO, i never knew it was all because of the great and
perfect work that he has been doing that is causing all this. so i
quickly contacted him, and he ask me some few questions and he said a
thing i will never forget that anyone who contacted him is always
getting his or her healing in just three weeks after doing all he ask
you,so I was amazed all the time i heard that from him, so I did all
things only to see that at the very day which he said i will be healed,
all the strength that has left me before rush back and i becomes very
strong and healthy, this disease almost take my life,so i want to
hospital to give the final test to the disease and the doctor said i am
HIV negative,I am every amazed and happy about the healing Dr OJUGO
gave to me from the help of his ancient herbs . you can contact Dr
OJUGO at his email and process your own healing too at:
(dr.ojugospellhome@gmail.com) his phone number +2349055637445 thanks
24
Lisboa Paulo Jorge
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Sep 27, 2016 @ 8:20 pm
Hi friends!
I am Lisboa Jorge by name and i want to use this great opportunity to share with you some great and amazing testimony of how i was cured from HERPES Virus with the help of Dr Molemen Herbal Medicine.
Over 2 years now i have been suffering and living in pain with this deadly virus Herpes, fear grew in my mind everyday as i heard there is no cure for it, but to me i knew that medical drugs was not the only option in treating viruses and infection, my greatest problem was that i was stocked in pain as the symptoms has circulated over my body.
Few Months ago i decided to get more information online concerning herpes,and while i was surfing the web, i came across some great testimonials from various people on how Dr Molemen has been using his herbal medicine to cure different disease, at first i was shocked as i have never heard of such thing before, and also i doubted if it was true as it never came up on media, these people gave out the email address of Dr Molemen and advised we contact him for any problem, though i was doubting him i decided to put a test on it, moreover it was the fist time for me to hear something like that, i copied the email address of Dr Molemen and i sent him a message about my health status and i also requested for his medicine in order for me to get good health, he gave me a responded after some hours and he told me the procedure involved in order for me to get his medicine, he also said to me he was going to send me some herbal liquid medicine which was going to take for 2 weeks and after 2 weeks i will be totally cured.
I went with Dr Molemen and i followed exactly as i was told by this man, after 3 to 5 days of communication i eventually received a package from the mailing service and that was the medicine sent by Dr Molemen.
I started taking the medicine as i was directed by Dr Molemen and after 2 weeks i also started seen some changes on my skin, and after a month passed i noticed that the rashes on my skin are cleared, i was surprised and i had a thought to myself again LIKE! IS THIS REALLY WORKING OUT? when i noticed this changes i contacted this Great Dr and i told him about it, he told me to go to the hospital and do some check up if the virus is still there, i actually went to the hospital on Friday to do some test on my blood and after 3 days the result came out that i was completely free from HERPES, still many people will not believe this, but it did really works.
Dr Molemen is a brave man and he is set to answer all human disease, today i am living in good health as just with a test i conquered my pain and sorrow, Please you can contact Dr Molemen for any problem with the email below:(drmolemenspiritualtemple@gmail.com) or (dr.molemenspiritualtemple@yahoo.com) or call him +2347036013351, Thanks for reading this!
25
Aggie
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Sep 27, 2016 @ 8:20 pm
I was diagnosed by a professional nurse at a local health clinic with a moderate case of scabies in October, 2015. I had developed an outbreak of numerous itchy red bumps, some with small whiteheads, across my groin area and inner thighs. I was prescribed to Dr Odia Herbalist Center to treat the outbreak, and it seemed to work, however a few bumps remained and I treated again a week later because i was not using it as he told me. I was not able to get rid of all of the bumps, and they spread to my legs and abdomen. I bagged up all of my clothing, and laundered the rest, drying everything at a laundromat on high heat. A few weeks later, I reached into a bag to grab out a shirt, and the next day I had a huge outbreak on both arms. I went to a second nurse, who diagnosed me with scabies event though she had never seen scabies before, basing her decisions upon my original diagnosis and treatment. I treated with Dr Odia Herbalist Center again and it seemed to work ok. I bought the Cream off the Dr Odia Herbalist Center and the Mitactin salve and spray and that seemed to work better. I threw out a couch, and a rug, and a set of sheets, and began cleaning everything on a daily basis. I mopped my floor, did laundry, covered my mattress with a mattress cover, and wiped it down everyday. My love and best friend got it too. My friend went to see a third nurse who told him he had Folliculitis, which is basically a bacterial staph infection of the hair follicles on the skin. Well I laughed at first not believing that two previous medical professionals could have been wrong, but I researched it online and was prescribed to Dr Odia Herbalist Center and sure enough, That the symptoms and bumps looked exactly like what we had. We immediately stopped using the mitactin form the hospital, and permeation on the skin, and stopped cleaning with the extreme clean. Instead we bought antibacterial herbs soap from Dr Odia and over the counter antibiotic cream. My love and I began scrubbing our entire bodies daily with the soap and an exfoliating sponge, and put cream on the red spots. It worked like a charm. Within a week everything had basically disappeared, except some spots that were obviously still healing. if you are having any type of this disease or infection kindly email doctor Odia for cure:(drodiaherbalistcenter@gmail.com )

Contact Dr Odia for any kind of disease like:
HIV
Hepatitis C
Herpes
Cancer
Lupus
Syphilis
STI (sexually transmitted infection)
STD (sexually transmitted disease).
26
Lisboa Paulo Jorge
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Sep 27, 2016 @ 11:23 pm
Hi friends!
I am Lisboa Jorge by name and i want to use this great opportunity to share with you some great and amazing testimony of how i was cured from HERPES Virus with the help of Dr Molemen Herbal Medicine.
Over 2 years now i have been suffering and living in pain with this deadly virus Herpes, fear grew in my mind everyday as i heard there is no cure for it, but to me i knew that medical drugs was not the only option in treating viruses and infection, my greatest problem was that i was stocked in pain as the symptoms has circulated over my body.
Few Months ago i decided to get more information online concerning herpes,and while i was surfing the web, i came across some great testimonials from various people on how Dr Molemen has been using his herbal medicine to cure different disease, at first i was shocked as i have never heard of such thing before, and also i doubted if it was true as it never came up on media, these people gave out the email address of Dr Molemen and advised we contact him for any problem, though i was doubting him i decided to put a test on it, moreover it was the fist time for me to hear something like that, i copied the email address of Dr Molemen and i sent him a message about my health status and i also requested for his medicine in order for me to get good health, he gave me a responded after some hours and he told me the procedure involved in order for me to get his medicine, he also said to me he was going to send me some herbal liquid medicine which was going to take for 2 weeks and after 2 weeks i will be totally cured.
I went with Dr Molemen and i followed exactly as i was told by this man, after 3 to 5 days of communication i eventually received a package from the mailing service and that was the medicine sent by Dr Molemen.
I started taking the medicine as i was directed by Dr Molemen and after 2 weeks i also started seen some changes on my skin, and after a month passed i noticed that the rashes on my skin are cleared, i was surprised and i had a thought to myself again LIKE! IS THIS REALLY WORKING OUT? when i noticed this changes i contacted this Great Dr and i told him about it, he told me to go to the hospital and do some check up if the virus is still there, i actually went to the hospital on Friday to do some test on my blood and after 3 days the result came out that i was completely free from HERPES, still many people will not believe this, but it did really works.
Dr Molemen is a brave man and he is set to answer all human disease, today i am living in good health as just with a test i conquered my pain and sorrow, Please you can contact Dr Molemen for any problem with the email below:(drmolemenspiritualtemple@gmail.com) or (dr.molemenspiritualtemple@yahoo.com) or call him +2347036013351, Thanks for reading this!

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